Cytokine gene therapy: Hopes and pitfalls

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New hopes for gene therapy

Hopes were running high at the end of the 20th century. The newly hatched internet economy took off, the Cold War was consigned to history, two separate teams were racing to sequence the human genome, and once that was in the databanks, surely we would understand much more about our diseases and develop new cures based on the genetic insights. And Al Gore might become US president and do someth...

متن کامل

Gene Therapy for Pancreatic Cancer: Specificity, Issues and Hopes

A recent death projection has placed pancreatic ductal adenocarcinoma as the second cause of death by cancer in 2030. The prognosis for pancreatic cancer is very poor and there is a great need for new treatments that can change this poor outcome. Developments of therapeutic innovations in combination with conventional chemotherapy are needed urgently. Among innovative treatments the gene therap...

متن کامل

Translational Approaches towards Cancer Gene Therapy: Hurdles and Hopes.

INTRODUCTION Of the cancer gene therapy approaches, gene silencing, suicide/apoptosis inducing gene therapy, immunogene therapy and targeted gene therapy are deemed to sub-stantially control the biological consequences of genomic changes in cancerous cells. Thus, a large number of clinical trials have been conducted against various malignancies. In this review, we will discuss recent translatio...

متن کامل

Nf - Κ B a Good Target for Cancer Therapy ? Hopes and Pitfalls

Preface NF-κB transcription factors play a key role in many physiological processes, such as innate and adaptive immune responses, cell proliferation, cell death, and inflammation. It has become clear that aberrant regulation of NF-κB and the signaling pathways that control its activity are involved in cancer development and progression, as well as in resistance to chemo-and radiotherapy. This ...

متن کامل

Cell Therapy for Traumatic Brain Injury: Opportunities and Pitfalls

Today, stem cell transplantation is a hot topic in scientific circles as a novel therapeutic approach to repair the structure and function of central nervous system. The safe and neuroprotective effects of cell therapy in models and traumatic brain injury patients were evaluated in many experimental and clinical studies in recent decade and somewhat promising results were provided to the scient...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Annals of Oncology

سال: 1999

ISSN: 0923-7534

DOI: 10.1023/a:1008304721889